Article
[Technical considerations for KRAS testing in colorectal cancer. The biologist's point of view].
Bulletin du cancer - 1 Dec 2009
Blons H, Laurent-Puig P
Abstract excerpt
Targeted therapy against the EGF receptor was shown to be effective in a subgroup of patients with KRAS wild-type colorectal cancer. Therefore, cetuximab (Erbitux) or panitumumab (Vectibix) obtained the authorization by the EMEA restricted to patients with KRAS wild-type tumours. KRAS mutational testing has become part of the standard care in patients treated with EGFR targeting therapy. Testing for KRAS...
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