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Article

Genetic susceptibility factors in a cohort of 38 patients with SAPHO syndrome: a study of PSTPIP2, NOD2, and LPIN2 genes.

The Journal of rheumatology - 1 Feb 2010

Hurtado-Nedelec Margarita, Chollet-Martin Sylvie, Chapeton Diana, Hugot Jean-Pierre, Hayem Gilles, Gérard Bénédicte

Abstract excerpt

OBJECTIVE: The SAPHO syndrome (synovitis, acne, pustulosis, hyperostosis, and osteitis) is a rare disorder that mainly affects bone and skin. Chronic multifocal osteitis is the main diagnostic feature. Genetic studies of HLA genes have shown no role for these class II antigens, whereas studies of 2 mouse models (cmo and Lupo) point to a role of the PSTPIP2 gene. We analyzed the PSTPIP2 gene in patients with SAPHO...

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Source

Identifiers

PMID: 20032092
DOI: 10.3899/jrheum.090456

Genes

PSTPIP2
LPIN2
NOD2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Genetic susceptibility factors in a cohort of 38 patients with SAPHO syndrome: a study of PSTPIP2, NOD2, and LPIN2 genes.PMID 20032092Read ↗

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