Article
Co-culture of epithelial cells and bacteria for investigating host-pathogen interactions.
Lab on a chip - 7 Jan 2010
Kim Jeongyun, Hegde Manjunath, Jayaraman Arul
Abstract excerpt
The human gastrointestinal (GI) tract is a unique environment in which intestinal epithelial cells and non-pathogenic (commensal) bacteria co-exist. This equilibrium is perturbed by the entry of pathogens into the GI tract. A key step in the infection process is the navigation of the pathogen through the commensal bacterial layer to attach to epithelial cells. It has been proposed that the microenvironment that...
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