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Article

Angiotensin-converting enzyme gene polymorphism in hypertensive rural population of Haryana, India

1 Jan 2009

Abstract excerpt

BACKGROUND: Essential hypertension is a complex genetic disorder influenced by diverse environmental factors. Of the various physiological pathways affecting the homeostasis of blood pressure, the renin-angiotensin system (RAS) is known to play a critical role. Angiotensin-I converting enzyme (ACE) is a significant component of RAS and an insertion/deletion (I/D) polymorphism in its gene has been implicated in...

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PMID: 20009302
DOI: 10.4103/0974-2700.55323

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