Article
Modified sequential multiplex PCR for determining capsular serotypes of invasive pneumococci recovered from Seville.
Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases - 1 Sept 2010
Iraurgui P, Torres M J, Gandia A, Vazquez I, Cabrera E G, Obando I, Garnacho J, Aznar J
Abstract excerpt
The heptavalent pneumococcal vaccine's introduction resulted in a decline in invasive disease caused by Streptococcus pneumoniae, but was accompanied by an increase in non-vaccine serotypes. We evaluated a modified scheme of the sequential multiplex PCRs adapted to the prevalence of serotypes in Seville (Spain) for determining capsular serotypes of S. pneumoniae invasive clinical isolates. In adults, the modified...
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