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Article

Glycogen synthase kinase 3 regulates PAX3–FKHR-mediated cell proliferation in human alveolar rhabdomyosarcoma cells

7 Dec 2009

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 19995556
DOI: 10.1016/j.bbrc.2009.12.017

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Related research

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Glycogen synthase kinase 3 regulates PAX3–FKHR-mediated cell proliferation in human alveolar rhabdomyosarcoma cellsPMID 19995556Read ↗

High Expression of the PAX3-FKHR Oncoprotein Is Required to Promote Tumorigenesis of Human MyoblastsSemantic proximity Read ↗

Effects of PAX3-FKHR on malignant phenotypes in alveolar rhabdomyosarcoma.Semantic proximity Read ↗

Genome-Wide Identification of PAX3-FKHR Binding Sites in Rhabdomyosarcoma Reveals Candidate Target Genes Important for Development and CancerSemantic proximity Read ↗

Identification of PAX3‐FKHR‐regulated genes differentially expressed between alveolar and embryonal rhabdomyosarcoma: Focus on <i>MYCN</i> as a biologically relevant targetSemantic proximity Read ↗

Proliferative and apoptotic differences between alveolar rhabdomyosarcoma subtypes: A comparative study of tumors containing PAX3‐FKHR or PAX7‐FKHR gene fusionsSemantic proximity Read ↗

Identification of a PAX-FKHR Gene Expression Signature that Defines Molecular Classes and Determines the Prognosis of Alveolar RhabdomyosarcomasSemantic proximity Read ↗

Acquisition of an oncogenic fusion protein serves as an initial driving mutation by inducing aneuploidy and overriding proliferative defects.Semantic proximity Read ↗

Defining the Cooperative Genetic Changes That Temporally Drive Alveolar RhabdomyosarcomaSemantic proximity Read ↗

Glycogen synthase kinase 3 inhibitors induce the canonical WNT/β-catenin pathway to suppress growth and self-renewal in embryonal rhabdomyosarcomaSemantic proximity Read ↗

Downregulation of microRNAs miR-1, -206 and -29 stabilizes PAX3 and CCND2 expression in rhabdomyosarcomaSemantic proximity Read ↗

Cell-type-specific regulation of distinct sets of gene targets by Pax3 and Pax3/FKHRSemantic proximity Read ↗

Kat3 coactivators in somatic stem cells and cancer stem cells: biological roles, evolution, and pharmacologic manipulationSemantic proximity Read ↗

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