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Article

In silico analysis of chimeric espA, eae and tir fragments of Escherichia coli O157:H7 for oral immunogenic applications.

Theoretical biology & medical modelling - 8 Dec 2009

Amani Jafar, Mousavi S Latif, Rafati Sima, Salmanian Ali H

Abstract excerpt

BACKGROUND: In silico techniques are highly suited for both the discovery of new and development of existing vaccines. Enterohemorrhagic Escherichia coli O157:H7 (EHEC) exhibits a pattern of localized adherence to host cells, with the formation of microcolonies, and induces a specific histopathological lesion (attaching/effacing). The genes encoding the products responsible for this phenotype are clustered on a...

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Identifiers

PMID: 19995413
DOI: 10.1186/1742-4682-6-28
PMCID: PMC3224939

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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