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Article

DNA sequence abnormalities of human glucose-6-phosphate dehydrogenase variants.

The Journal of biological chemistry - 5 Mar 1991

Beutler E, Kuhl W, Gelbart T, Forman L

Abstract excerpt

Over 400 supposedly biochemically and genetically distinct variants of glucose-6-phosphate dehydrogenase (G6PD) have been described in the past. In order to investigate these variants at the DNA sequence level we have now determined the relevant sequences of introns of G6PD and describe a method which allows us to rapidly determine the sequence of the entire coding region of G6PD. This technique was applied to...

Topics

Anemia, Hemolytic, Congenital Nonspherocytic
Base Sequence
Genes
Glucosephosphate Dehydrogenase
Humans
Introns
Molecular Sequence Data
Mutation
Oligonucleotides
Polymerase Chain Reaction

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PMID: 1999409

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1999409-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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