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Article

Molecular genetic analysis of factor X deficiency: gene deletion and germline mosaicism.

Human genetics - 1 Jan 1991

Wieland K, Millar D S, Grundy C B, Mibashan R S, Kakkar V V, Cooper D N

Abstract excerpt

A case of homozygous factor X deficiency arising from the inheritance of two non-identical gene deletions from heterozygous parents is described. One, a partial gene deletion, was localized to exons VII and VIII by a combination of Southern blotting and polymerase chain reaction (PCR) amplification of exon sequences. The other deletion, of maternal origin, probably involves the entire factor X gene. Restriction...

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PMID: 1997381
DOI: 10.1007/BF00202408

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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