Article
BOAT: Basic Oligonucleotide Alignment Tool.
BMC genomics - 3 Dec 2009
Zhao Shu-Qi, Wang Jun, Zhang Li, Li Jiong-Tang, Gu Xiaocheng, Gao Ge, Wei Liping
Abstract excerpt
BACKGROUND: Next-generation DNA sequencing technologies generate tens of millions of sequencing reads in one run. These technologies are now widely used in biology research such as in genome-wide identification of polymorphisms, transcription factor binding sites, methylation states, and transcript expression profiles. Mapping the sequencing reads to reference genomes efficiently and effectively is one of the...
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