Article
The transcript elongation factor FACT affects Arabidopsis vegetative and reproductive development and genetically interacts with HUB1/2.
The Plant journal : for cell and molecular biology - 1 Feb 2010
Lolas Ihab B, Himanen Kristiina, Grønlund Jesper T, Lynggaard Carina, Houben Andreas, Melzer Michael, Van Lijsebettens Mieke, Grasser Klaus D
Abstract excerpt
The facilitates chromatin transcription (FACT) complex, consisting of the SSRP1 and SPT16 proteins, is a histone chaperone that assists the progression of transcribing RNA polymerase on chromatin templates by destabilizing nucleosomes. Here, we examined plants that harbour mutations in the genes encoding the subunits of Arabidopsis FACT. These experiments revealed that (i) SSRP1 is critical for plant viability,...
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