Article
Association of p73 G4C14-to-A4T14 polymorphism at exon 2 with the response of human lung adenocarcinoma cell lines to chemotherapy.
Cell biology international - 25 Jan 2010
Liu Kaishan, Jiang Lucen, Zhou Xulong
Abstract excerpt
In order to assess the effect of p73 gene polymorphism G4C14-A4T14 on cisplatin-based chemosensitivity of human lung adenocarcinoma cell lines, we examined the differences in biological character and drug sensitivity affected by cisplatin between human lung adenocarcinoma cell lines A549 and P15. The allelic expression of p73 in A549 and P15 was studied by Sty I polymorphism analysis. MTT...
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