Article
A comprehensive sensitivity analysis of microarray breast cancer classification under feature variability.
BMC bioinformatics - 26 Nov 2009
Sontrop Herman M J, Moerland Perry D, van den Ham René, Reinders Marcel J T, Verhaegh Wim F J
Abstract excerpt
BACKGROUND: Large discrepancies in signature composition and outcome concordance have been observed between different microarray breast cancer expression profiling studies. This is often ascribed to differences in array platform as well as biological variability. We conjecture that other reasons for the observed discrepancies are the measurement error associated with each feature and the choice of preprocessing...
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