Article
Studies on long-term infection of human cells with Porcine endogenous retrovirus.
Acta virologica - 1 Jan 2009
Yu P, Zhang P, Zhang L, Li S F, Cheng J Q, Lu Y R, Li Y P, Bu H
Abstract excerpt
A major concern in pig-to-human xenotransplantations is the potential risk of transmission of Porcine endogenous retroviruses (PERVs) integrated in the pig genome. Our previous work has shown that PERV provirus genes and gag protein can be detected in human embryonic kidney HEK-293 cells during a long-term infection with PERV (Yu et al., Transplant. Proc. 37, 496-499, 2005). In this study, we continued studying...
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