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Colorectal cancer cell-derived microvesicles are enriched in cell cycle-related mRNAs that promote proliferation of endothelial cells

25 Nov 2009

Abstract excerpt

BACKGROUND: Various cancer cells, including those of colorectal cancer (CRC), release microvesicles (exosomes) into surrounding tissues and peripheral circulation. These microvesicles can mediate communication between cells and affect various tumor-related processes in their target cells. RESULTS: We present potential roles of CRC cell-derived microvesicles in tumor progression via a global comparative...

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PMID: 19930720
DOI: 10.1186/1471-2164-10-556

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