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Article

Tumor mapping in 2 large multigenerational families with CYLD mutations: implications for disease management and tumor induction.

Archives of dermatology - 1 Nov 2009

Rajan Neil, Langtry James A A, Ashworth Alan, Roberts Catherine, Chapman Pam, Burn John, Trainer Alison H

Abstract excerpt

OBJECTIVES: To comprehensively ascertain the extent and severity of clinical features in affected individuals from 2 large families with proven heterozygous mutations in the CYLD locus and to correlate these findings with the 3 appendageal tumor predisposition syndromes (familial cylindromatosis, Brooke-Spiegler syndrome, and multiple familial trichoepitheliomas) known to be associated with such germline...

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Source

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Identifiers

PMID: 19917957
DOI: 10.1001/archdermatol.2009.262
PMCID: PMC2935681

Genes

CYLD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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