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Article

Efficacy of posaconazole against three clinical Aspergillus fumigatus isolates with mutations in the cyp51A gene.

Antimicrobial agents and chemotherapy - 1 Feb 2010

Mavridou Eleftheria, Brüggemann Roger J M, Melchers Willem J G, Mouton Johan W, Verweij Paul E

Abstract excerpt

The in vivo efficacy of posaconazole against 4 clinical Aspergillus fumigatus isolates with posaconazole MICs ranging from 0.03 to 16 mg/liter, as determined by CLSI method M38A, was assessed in a nonneutropenic murine model of disseminated aspergillosis. The underlying resistance mechanisms of t...

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Identifiers

PMID: 19917751
DOI: 10.1128/AAC.00931-09
PMCID: PMC2812170

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19917751-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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