Article
[Molecular research methods in the detection of germinal mutations in hereditary colorectal cancer].
Revista de gastroenterologia del Peru : organo oficial de la Sociedad de Gastroenterologia del Peru - 1 Jan 2000
Dominguez M V, Bastos E P, Silva S D, Rossi B M
Abstract excerpt
Colorectal cancer (CRC) is one of the main causes of death in South American countries. The hereditary forms of CRC are, familial adenomatous (FAP) and hereditary nonpolyposis colorectal cancer (HNPCC) or Lynch Syndrome (LS), which is the most common form. The detection of mutations in the DNA repair genes (MMR) and in the APC genes enables the development of prevention strategies. Some of these methods for...
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