Article
Epidemiology, variable genetic organization and regulation of the EDIN-B toxin in Staphylococcus aureus from bacteraemic patients.
Microbiology (Reading, England) - 1 Mar 2010
Franke Gefion C, Böckenholt Alexandra, Sugai Motoyuki, Rohde Holger, Aepfelbacher Martin
Abstract excerpt
EDIN-B (epidermal cell differentiation inhibitor-B; also termed C3Stau) is an exotoxin of Staphylococcus aureus which ADP-ribosylates and inactivates Rho GTP binding proteins. The EDIN-B gene (edin-B) and the gene for exfoliative toxin D (etd) make up the central part of a recently described pathogenicity island. Here we evaluated the prevalence and genetic organization of the edin-B/etd pathogenicity island in...
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