Article
A homozygous CARD9 mutation in a family with susceptibility to fungal infections.
The New England journal of medicine - 29 Oct 2009
Glocker Erik-Oliver, Hennigs Andre, Nabavi Mohammad, Schäffer Alejandro A, Woellner Cristina, Salzer Ulrich, Pfeifer Dietmar, Veelken Hendrik, Warnatz Klaus, Tahami Fariba, Jamal Sarah, Manguiat Annabelle, Rezaei Nima, Amirzargar Ali Akbar, Plebani Alessandro, Hannesschläger Nicole, Gross Olaf, Ruland Jürgen, Grimbacher Bodo
Abstract excerpt
BACKGROUND: Chronic mucocutaneous candidiasis may be manifested as a primary immunodeficiency characterized by persistent or recurrent infections of the mucosa or the skin with candida species. Most cases are sporadic, but both autosomal dominant inheritance and autosomal recessive inheritance have been described. METHODS: We performed genetic studies in 36 members of a large, consanguineous five-generation...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.