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Malaria Diagnosis by a Polymerase Chain Reaction–Based Assay Using a Pooling Strategy

27 Oct 2009

Abstract excerpt

Pooling clinical specimens reduces the number of assays needed when screening for infectious diseases. Polymerase chain reaction (PCR)-based assays are the most sensitive tests to diagnose malaria, but its high cost limits its use. We adapted a pooling platform that could reduce the number of assays needed to detect malaria infection. To evaluate this platform, two sets of 100 serum samples, with 1% and 5%...

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PMID: 19861605
DOI: 10.4269/ajtmh.2009.09-0274

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