Article
Fitting mixture distributions to phenylthiocarbamide (PTC) sensitivity.
American journal of human genetics - 1 Jan 1991
Jones P N, McLachlan G J
Abstract excerpt
A technique for fitting mixture distributions to phenylthiocarbamide (PTC) sensitivity is described. Under the assumptions of Hardy-Weinberg equilibrium, a mixture of three normal components is postulated for the observed distribution, with the mixing parameters corresponding to the proportions of the three genotypes associated with two alleles A and a acting at a single locus. The corresponding genotypes AA, Aa,...
Topics
- Algorithms
- Alleles
- Binomial Distribution
- Genotype
- Humans
- Models, Genetic
- Phenylthiourea
- Taste Threshold