Article
Phenotypic and genotypic characterization of Enterobacteriaceae with decreased susceptibility to carbapenems: results from large hospital-based surveillance studies in China.
Antimicrobial agents and chemotherapy - 1 Jan 2010
Yang Qiwen, Wang Hui, Sun Hongli, Chen Hongbin, Xu Yingchun, Chen Minjun
Abstract excerpt
The resistance mechanism of 49 Enterobacteriaceae isolates with decreased susceptibility to carbapenems collected from 2004 to 2008 at 16 teaching hospitals in China was investigated. Moderate- to high-level carbapenem resistance in most isolates was more closely associated with loss or decreased expression of both major porins combined with production of AmpC or extended-spectrum beta-lactamase enzymes, while...
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