Article
Human gut microbiome adopts an alternative state following small bowel transplantation.
Proceedings of the National Academy of Sciences of the United States of America - 6 Oct 2009
Hartman Amber L, Lough Denver M, Barupal Dinesh K, Fiehn Oliver, Fishbein Thomas, Zasloff Michael, Eisen Jonathan A
Abstract excerpt
Small bowel transplants provide an exceptional opportunity for long-term study of the microbial ecology of the human small bowel. The ileostomy created at time of transplant for ongoing monitoring of the allograft provides access to samples of ileal effluent and mucosal biopsies. In this study, we used qPCR to assay the bacterial population of the small bowel lumen of 17 small bowel transplant patients over time....
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