Article
Emergence of hepatitis C virus genotype 4: phylogenetic analysis reveals three distinct epidemiological profiles.
Journal of clinical microbiology - 1 Dec 2009
de Bruijne Joep, Schinkel Janke, Prins Maria, Koekkoek Sylvie M, Aronson Sem J, van Ballegooijen Marijn W, Reesink Hendrik W, Molenkamp Richard, van de Laar Thijs J W
Abstract excerpt
Hepatitis C virus (HCV) genotype 4 (HCV-4) infection is considered to be difficult to treat and has become increasingly prevalent in European countries, including The Netherlands. Using a molecular epidemiological approach, the present study investigates the genetic diversity and evolutionary origin of HCV-4 in Amsterdam, The Netherlands. Phylogenetic analysis of the NS5B sequences (668 bp) obtained from 133...
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