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Article

Senescent cultures of human dermal fibroblasts modified phenotype when immobilized in fibrin polymer.

Journal of biomaterials science. Polymer edition - 1 Jan 2009

Acevedo Cristian A, Brown Donald I, Young Manuel E, Reyes Juan G

Abstract excerpt

One of the limitations in tissue engineering is the restricted ability to expand the number of cells, because somatic cells can duplicate a limited number of times before they lose the ability to divide, leading to a senescent state. Here we report that the interaction of senescent fibroblasts wi...

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PMID: 19793448
DOI: 10.1163/156856208X394418

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19793448-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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