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Molecular epidemiology of Clostridium difficile over the course of 10 years in a tertiary care hospital.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America - 15 Oct 2009

Belmares Jaime, Johnson Stuart, Parada Jorge P, Olson Mary M, Clabots Connie R, Bettin Kristine M, Peterson Lance R, Gerding Dale N

Abstract excerpt

BACKGROUND: The molecular epidemiology of endemic and outbreak Clostridium difficile strains across time is not well known. METHODS: HindIII restriction endonuclease analysis (REA) typing was performed on available clinical C. difficile isolates from 1982 to 1991. RESULTS: The annual incidence of C. difficile infection (CDI) ranged from 3.2 to 9.9 cases per 1000 discharges and was significantly higher in 1982,...

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PMID: 19780659
DOI: 10.1086/605638

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