Article
Sex differences in the effects of inherited bitter thiourea sensitivity on body weight in 4-6-year-old children.
Obesity (Silver Spring, Md.) - 1 Jun 2010
Keller Kathleen L, Reid Adrienne, MacDougall Megan C, Cassano Hope, Song Joo Lee, Deng Liyong, Lanzano Patricia, Chung Wendy K, Kissileff Harry R
Abstract excerpt
Previous studies have shown that inherited taste blindness to bitter compounds like 6-n-propylthiouracil (PROP) may be a risk factor for obesity, but this literature has been highly controversial. The objectives of this study were (i) to confirm findings that show an interaction between PROP status and sex on BMI z-score, and (ii) to determine if sex also interacts with variations in TAS2R38 (phenylthiocarbamide...
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