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Article

[Fetal cell carcinogenesis hypothesis and the prospect of future laboratory tests].

Rinsho byori. The Japanese journal of clinical pathology - 1 Aug 2009

Takano Toru

Abstract excerpt

A novel hypothesis of carcinogenesis, the "fetal cell carcinogenesis" hypothesis, was established based on molecular evidence of thyroid carcinoma. In this hypothesis, cancer cells are derived directly from the remnants of fetal cells, instead of well-differentiated somatic cells by de-differentiation. For example, thyroid cancer cells are generated from three types of fetal thyroid cell, namely, thyroid stem...

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Identifiers

PMID: 19764411

Genes

BRAF
PAX8
RET

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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