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Article

[Molecular mechanism of thyroid carcinogenesis].

Nihon rinsho. Japanese journal of clinical medicine - 1 Nov 2007

Yamashita Shunichi, Mitsutake Norisato

Abstract excerpt

Molecular mechanism of thyroid carcinogenesis has been well studied through the discovery of genetic abnormalities such as RET/PTC rearrangement and BRAF mutation, both of which constitutively activate MAP kinase pathway and are frequently found in papillary thyroid cancer. The TP53 mutation is thought to play a critical role in transformation of differentiated thyroid cancer into anaplastic thyroid cancer....

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Source

Identifiers

PMID: 18018555

Genes

BRAF
RET

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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