Article
Parentage analysis by endonuclease shattering of hypervariable DNA.
Transfusion - 1 Sept 1990
Chiafari F A, Wenk R E
Abstract excerpt
Single-locus DNA probes for tandem repeat sequences are now used in conjunction with particular endonucleases to characterize heritable restriction fragment lengths in parentage tests. Southern blots of this type, however, demonstrate only two attributes of an allele: its length and the presence...
Topics
- Alleles
- Base Sequence
- Blotting, Southern
- DNA
- DNA Probes
- DNA Restriction Enzymes
- Endonucleases
- Genetic Carrier Screening
- Humans
- Male
- Paternity
- Phenotype
- Polymorphism, Restriction Fragment Length