Article
Core myopathies and risk of malignant hyperthermia.
Anesthesia and analgesia - 1 Oct 2009
Klingler Werner, Rueffert Henrik, Lehmann-Horn Frank, Girard Thierry, Hopkins Philip M
Abstract excerpt
In this article, we analyze myopathies with cores, for which an association to malignant hyperthermia (MH) has been suggested. We discuss the clinical features, the underlying genetic defects, subsequent effects on cellular calcium metabolism, and in vitro muscle responses to MH triggers. We describe in detail central core disease, multiminicore disease, and nemaline rod myopathy. We categorize the diseases...
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