Article
Defining the pathogenic role of telomerase mutations in myelodysplastic syndrome and acute myeloid leukemia
2 Sept 2009
Abstract excerpt
The primary pathology in many cases of myelodysplasia (MDS) and acute myeloid leukemia (AML) remains unknown. In some cases, two or more affected members have been identified in the same family. To date, mutations in two genes have been directly implicated: the hematopoietic transcription factors RUNX1 (runt-related transcription factor 1) and CEBPA (CCATT-box enhancer binding protein alpha). However, there are...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.