Elucidating the genetics and pathology of Perry syndrome.

Abstract excerpt

Perry syndrome is characterized clinically by autosomal dominantly inherited, rapidly progressive parkinsonism, depression, weight loss and hypoventilation. In the seven families reported previously and the two new families presented herein (the Hawaii family and the Fukuoka-4 Japanese family), the mean disease onset age is 48 years (range: 35-61) and the mean disease duration five years (range: 2-10). Histology...

Topics

Join the communities discussing this publication.

• Hypoventilation
• Chlorocebus aethiops
• Depression
• Dynactin Complex
• Glycine