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Article

The molecular defect of albumin Castel di Sangro: 536 Lys----Glu.

Biochimica et biophysica acta - 19 Jun 1990

Minchiotti L, Galliano M, Iadarola P, Zepponi E, Ferri G

Abstract excerpt

Albumin Castel di Sangro is a rare fast-moving variant of human serum albumin which has been discovered in heterozygous form in the serum of an 85-year-old woman living in Castel di Sangro (Abruzzo, Italy). Isoelectric focusing analysis of CNBr fragments from the purified variant allowed us to localize the mutation in fragment CNBr VI (residues 447-548). This fragment was isolated on a preparative scale and...

Topics

Chromatography, High Pressure Liquid
Cyanogen Bromide
Genetic Variation
Glutamates
Glutamic Acid
Humans
Lysine
Mutation
Peptide Fragments
Serum Albumin
Serum Albumin, Human

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Trypsin

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Identifiers

PMID: 1973054
DOI: 10.1016/0167-4838(90)90187-k

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1973054-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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