Article
Structural characterization of a glycoprotein variant of human serum albumin: albumin Casebrook (494 Asp----Asn).
Biochimica et biophysica acta - 26 Jul 1991
Peach R J, Brennan S O
Abstract excerpt
Albumin Casebrook is an electrophoretically slow genetic variant of human albumin with a relative molecular mass 2.5 kDa higher than normal albumin. It constitutes about 35% of total serum albumin in heterozygous carriers. The decrease in negative charge observed on incubation with sialidase suggested the presence of a carbohydrate moiety and the normalization of molecular weight following treatment with Endo-F...
Topics
- Amino Acid Sequence
- Amino Acids
- Chromatography, Ion Exchange
- Electrophoresis, Agar Gel
- Electrophoresis, Polyacrylamide Gel
- Genetic Variation
- Humans
- Molecular Sequence Data
- Serum Albumin