Article
The functional impairment of natural killer cells during influenza virus infection.
Immunology and cell biology - 1 Jan 2000
Guo Hailong, Kumar Pawan, Moran Thomas M, Garcia-Sastre Adolfo, Zhou Yan, Malarkannan Subramaniam
Abstract excerpt
Natural killer (NK) cells have a critical role in clearing influenza virus, which primarily infects the lung epithelial cells. However, the ability of influenza virus to infect and manipulate NK cells has not been studied. In this context, we hypothesized that influenza virus can target NK cells leading to a functional impairment in their ability to mediate cytotoxicity and cytokine/chemokine generations. Here,...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.