Article
Facilitated oligomerization of mycobacterial GroEL: evidence for phosphorylation-mediated oligomerization.
Journal of bacteriology - 1 Nov 2009
Kumar C M Santosh, Khare Garima, Srikanth C V, Tyagi Anil K, Sardesai Abhijit A, Mande Shekhar C
Abstract excerpt
The distinctive feature of the GroES-GroEL chaperonin system in mediating protein folding lies in its ability to exist in a tetradecameric state, form a central cavity, and encapsulate the substrate via the GroES lid. However, recombinant GroELs of Mycobacterium tuberculosis are unable to act as...
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