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Article

Mutations in ribonucleic acid binding protein gene cause familial dilated cardiomyopathy.

Journal of the American College of Cardiology - 1 Sept 2009

Brauch Katharine M, Karst Margaret L, Herron Kathleen J, de Andrade Mariza, Pellikka Patricia A, Rodeheffer Richard J, Michels Virginia V, Olson Timothy M

Abstract excerpt

OBJECTIVES: We sought to identify a novel gene for dilated cardiomyopathy (DCM). BACKGROUND: DCM is a heritable, genetically heterogeneous disorder that remains idiopathic in the majority of patients. Familial cases provide an opportunity to discover unsuspected molecular bases of DCM, enabling pre-clinical risk detection. METHODS: Two large families with autosomal-dominant DCM were studied. Genome-wide linkage...

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Topics

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Share to Cardiomyopathy, Dilated
Share to Genetic Linkage

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Mutation, Missense

Share to Myocardium

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Source

Open in PubMed Open full text

Identifiers

PMID: 19712804
DOI: 10.1016/j.jacc.2009.05.038
PMCID: PMC2782634

Genes

RBM20

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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