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Article

Chronic Dietary Exposure to a Low-Dose Mixture of Genistein and Vinclozolin Modifies the Reproductive Axis, Testis Transcriptome, and Fertility

1 Apr 2009

Abstract excerpt

BACKGROUND: The reproductive consequences and mechanisms of action of chronic exposure to low-dose endocrine disruptors are poorly understood. OBJECTIVE: We assessed the effects of a continuous, low-dose exposure to a phytoestrogen (genistein) and/or an antiandrogenic food contaminant (vinclozolin) on the male reproductive tract and fertility. METHODS: Male rats were exposed by gavage to genistein and vinclozolin...

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Share to Carcinogens and Genotoxicity Assessment
Share to Effects and risks of endocrine disrupting chemicals
Share to Phytoestrogen effects and research

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Identifiers

PMID: 19672408
DOI: 10.1289/ehp.0800158

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