Article
TRPA channels distinguish gravity sensing from hearing in Johnston's organ.
Proceedings of the National Academy of Sciences of the United States of America - 11 Aug 2009
Sun Yishan, Liu Lei, Ben-Shahar Yehuda, Jacobs Julie S, Eberl Daniel F, Welsh Michael J
Abstract excerpt
Although many animal species sense gravity for spatial orientation, the molecular bases remain uncertain. Therefore, we studied Drosophila melanogaster, which possess an inherent upward movement against gravity-negative geotaxis. Negative geotaxis requires Johnston's organ, a mechanosensory structure located in the antenna that also detects near-field sound. Because channels of the transient receptor potential...
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