Article
CYP1B1, a developmental gene with a potential role in glaucoma therapy.
Xenobiotica; the fate of foreign compounds in biological systems - 1 Aug 2009
Choudhary D, Jansson I, Schenkman J B
Abstract excerpt
The association of CYP1B1 gene alterations in primary congenital glaucoma individuals has been known for about a decade. Recent evidence has shown the involvement of CYP1B1 mutations in a number of forms of glaucoma and anterior segment disorders. This suggests a wide role for CYP1B1 in ocular physiology. Histochemical studies of eyes from individuals with primary congenital glaucoma revealed abnormalities in the...
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