Article
Expansion of CAG repeats in the spinocerebellar ataxia type 1 (SCA1) gene in idiopathic oligozoospermia patients.
Journal of assisted reproduction and genetics - 1 May 2009
Lai Yen-Chein, Wang Wen-Chung, Yang Jiann-Jou, Li Shuan-Yow
Abstract excerpt
PURPOSE: The lengths of CAG repeats in two spinocerebellar ataxia genes, SCA1 and SCA3, were analyzed to determine whether such repeats exist in higher numbers in infertile males. METHODS: Blood samples were collected from healthy controls, oligozoospermia patients, and azoospermia patients. DNA fragments containing target CAG repeats were amplified by PCR with template DNA purified from the blood samples. CAG...
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