Article
A Multiparent Advanced Generation Inter-Cross to fine-map quantitative traits in Arabidopsis thaliana.
PLoS genetics - 1 Jul 2009
Kover Paula X, Valdar William, Trakalo Joseph, Scarcelli Nora, Ehrenreich Ian M, Purugganan Michael D, Durrant Caroline, Mott Richard
Abstract excerpt
Identifying natural allelic variation that underlies quantitative trait variation remains a fundamental problem in genetics. Most studies have employed either simple synthetic populations with restricted allelic variation or performed association mapping on a sample of naturally occurring haplotypes. Both of these approaches have some limitations, therefore alternative resources for the genetic dissection of...
Topics
- Arabidopsis
- Bayes Theorem
- Chromosome Mapping
- Crosses, Genetic
- Founder Effect
- Genome-Wide Association Study
- Linkage Disequilibrium
- Models, Genetic
- Phenotype
- Plants, Genetically Modified
- Polymorphism, Single Nucleotide
- Quantitative Trait Loci