Article
Recombinant 8 syndrome: the pool of Hispanic pericentric inversion 8 carriers expands numerically and geographically.
American journal of obstetrics and gynecology - 1 Nov 1991
Izquierdo L A, McConnell T S, Curet L B, Sarto G E
Abstract excerpt
Recombinant 8 syndrome is a well-established syndrome with mental and developmental retardation and usually severe cardiac anomalies. A carrier parent will produce affected offspring in 6% of pregnancies and carrier offspring in 53% of such pregnancies. Four New Mexican kindres ascertained by the...
Topics
- Chromosome Aberrations
- Chromosome Disorders
- Chromosomes, Human, Pair 8
- Colorado
- Face
- Female
- Gene Frequency
- Heart Defects, Congenital
- Hispanic or Latino
- Humans
- Intellectual Disability
- Male
- Mutation
- New Mexico
- Risk