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Article

Mechanisms underlying Andersen's syndrome pathology in skeletal muscle are revealed in human myotubes.

American journal of physiology. Cell physiology - 1 Oct 2009

Sacconi S, Simkin D, Arrighi N, Chapon F, Larroque M M, Vicart S, Sternberg D, Fontaine B, Barhanin J, Desnuelle C, Bendahhou S

Abstract excerpt

Andersen's syndrome is a rare disorder that has been defined with a triad: periodic paralysis, cardiac arrhythmia, and development anomalies. Muscle weakness has been reported in two-thirds of the patients. KCNJ2 remains the only gene linked to Andersen's syndrome; this gene encodes for the alpha-subunit of the strong inward-rectifier K+ channel Kir2.1. Several studies have shown that Andersen's syndrome...

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Source

Identifiers

PMID: 19570891
DOI: 10.1152/ajpcell.00519.2008

Genes

KCNJ2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Mechanisms underlying Andersen's syndrome pathology in skeletal muscle are revealed in human myotubes.PMID 19570891Read ↗

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