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Article

Mitochondrial DNA depletion in progressive external ophthalmoplegia caused by POLG1 mutations.

Acta neurologica Scandinavica. Supplementum - 1 Jan 2009

Tzoulis C, Papingji M, Fiskestrand T, Røste L S, Bindoff L A

Abstract excerpt

OBJECTIVES: To investigate two patients with late onset, progressive external ophthalmoplegia (PEO) and sensory peripheral neuropathy. MATERIALS & METHODS: The patients aged 86 and 50 years were investigated clinically including magnetic resonance imaging of the brain, electrophysiological studies and, in one, skeletal muscle biopsy. Molecular studies included sequencing of the whole coding region of the POLG1...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 19566497
DOI: 10.1111/j.1600-0404.2009.01212.x

Genes

POLG

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Mitochondrial DNA depletion in progressive external ophthalmoplegia caused by POLG1 mutations.PMID 19566497Read ↗

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