Article
Increased serum neopterin concentration as indicator of disease severity and poor survival in multiple myeloma.
European journal of haematology - 1 Oct 1991
Boccadoro M, Battaglio S, Omedè P, Palumbo A P, Fusaro A, Frieri R, Gallone G, Polloni R, Mosso R, De Filippi P G
Abstract excerpt
In this study we investigated serum neopterin levels in 73 multiple myeloma (MM) patients (63 determinations at diagnosis, 58 in remission, and 35 at relapse), in 56 monoclonal gammopathies of undetermined significance (MGUS), and in 70 normal controls. Median neopterin level was 5.3 nmol/l in normal controls, 6.8 nmol/l in MGUS, and 10.7 nmol/l in MM patients. In comparison to healthy subjects, significantly...
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