Article
Aquagenic palmar wrinkling as a presenting feature of cystic fibrosis gene dysfunction.
Clinical and experimental dermatology - 1 Dec 2009
Stewart L C, Doe S J, Bourke S J, Leech S
Abstract excerpt
Aquagenic palmar wrinkling (APW) is characterized by the rapid and transient oedematous wrinkling of the palms after brief immersion in water. APW has been associated with cystic fibrosis (CF). Since the discovery of the CF gene, the clinical spectrum of CF has broadened from classic severe CF to include milder 'atypical CF' and 'CF-related disorders'. We report an unusual case in which APW occurred in a patient...
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