Article
Apolipoprotein E Arg136 --> Cys in individuals with premature myocardial infarction.
Folia biologica - 1 Jan 2009
Hubácek J A, Poledne R, Pitha J, Aschermann M, Skalická H, Stanek V
Abstract excerpt
Coronary artery disease is a serious health problem worldwide caused by interactions between genetic and environmental risk factors. One of the candidate genes is the gene for apolipoprotein E. We present a case report of two young smoking and obese carriers (man 45 years and woman 32 years old) of the apolipoprotein E (p.Arg136Cys) mutation, but with no severe dyslipidaemias detected among 1,671 survivors (1,483...
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